BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2015-00057 GA29144 - A PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF
ETROLIZUMAB AS AN INDUCTION AND MAINTENANCE TREATMENT FOR PATIENTS WITH M More ...
clinical trial drugs phase 3 multicentric C Prof. Dr. Stephan Brand F. Hoffmann-La Roche Ltd. Kantonsspital St. Gallen, St. Gallen
Inselspital Bern, Bern
Crohn-Colitis Zentrum Bern, Bern
Universitätsspital Zürich, Zürich
Ethikkommission Ostschweiz (EKOS) Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 15.03.2016 Study has ended
2015-00056 The role of brain metabolism in human sleep-wake regulation non clinical, involving persons monocentric A Prof. Dr. med. Erich Seifritz Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich
Kantonale Ethikkommission Zürich 29.03.2016
2015-00055 Assessment of psychological and metabolic responses during fructose intolerance breath tests in patients with functional GI disorders: placebo-controlled breath testing clinical trial other clinical trials monocentric A Dr. med Clive Wilder-Smith Brain-Gut Research Group/Gastroenterology Group Practice Brain-Gut-Research Group/Gastroenterology Group Practice, Bern
Kantonale Ethikkommission Bern 17.05.2016 Study has ended
2015-00053 Validation of clinical signs non clinical, involving persons multicentric A Dr. med. Selma Aybek Service de Neurologie, Hospitalier Universitaire Genève (HUG) Clinic of Neurology, HUG, Geneva
Neurological Clinic, KSA, Aarau
Commission Cantonale d'éthique de la recherche Genève (CCER) Ethikkommission Nordwest- und Zentralschweiz EKNZ 25.01.2016 Study has ended
2015-00052 Ergebnisse der kombinierten dorso-ventralen operativen Versorgung thorakolumbaler Wirbelkörperfrakturen personal data/biological material monocentric Prof. Dr. med. Alex Alfieri Kantonsspital Winterthur Kantonsspital Winterthur, 8401 Winterthur
Kantonale Ethikkommission Zürich 12.01.2016
2015-00051 Belastete Röntgen versus "gravity-stress" Aufnahmen in der konservativen Therapie lateraler Malleolarfrakturen, 1 Jahres Ergebnisse non clinical, involving persons monocentric A PD Dr. med. Fabian Krause Inselspital Bern Universitätsklinik für Orthopädische Chirurgie, Bern
Kantonale Ethikkommission Bern 18.02.2016
2015-00050 Implementation of a non-coding RNAs quantification method in blood non clinical, involving persons monocentric A Dr Maurice Beaumont, MD, PhD Nestlé Institute of Health Science (NIHS) Nestlé Research Center, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 23.11.2015 Study has ended
2015-00049 "Cervical Range of Motion in Neck pain patients: A mixed methods study"
(Beweglichkeit der Halswirbelsäule von Nackenschmerzpatienten)
non clinical, involving persons monocentric A Dr. Jaap Swaneburg Balgrist University Clinic Balgrist University Clinic, Zurich
Kantonale Ethikkommission Zürich 18.01.2016 Study has ended
2015-00044 M13-549: A Phase III, Randomized, Double-Blind Study Comparing ABT-494 to Placebo in Subjects with Moderately to Severely Active Rheumatoid Arthritis Who Are on a Stable Dose of Conventional Synthetic More ... clinical trial drugs phase 3 multicentric C Prof. Dr. Jean Dudler AbbVie AG HFR Kantonsspital Freiburg, Rheumatologie, 1708 Freiburg
Kantonsspital Aarau, Abteilung Rheumatologie, Aarau
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Ethikkommission Nordwest- und Zentralschweiz EKNZ 23.02.2016 Study has ended
2015-00043 M13-545: A Phase 3, Randomized, Double-Blind Study Comparing ABT-494 Once Daily Monotherapy to Methotrexate (MTX) Monotherapy in MTX-Naïve Subjects with Moderately to Severely Active Rheumatoid Arthri More ... clinical trial drugs phase 3 monocentric C Prof. Dr. Jean Dudler AbbVie AG Service de rhumatologie HFR Fribourg – Hôpital Cantonal, Fribourg
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 14.03.2016 Study has ended
2015-00042 SAKK 16/14
Anti-PD-L1 antibody MEDI4736 in addition to neoadjuvant chemotherapy in patients with stage IIIA(N2) non-small cell lung cancer (NSCLC). A multicenter single-arm phase II trial.
clinical trial drugs phase 2 multicentric C Dr. med. Sacha Rothschild SAKK Universitätsspital Basel, Basel
Inselspital Bern, Bern
Spital STS AG Thun, Thun
Kantonspital Aarau, Aarau
Kantonsspital Baden, Baden
Luzerner Kantonsspital, Luzern
St. Claraspital, Basel
Hôpitaux Univ More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 30.03.2016
2015-00041 Factors predicting the forgotten joint score after total knee arthroplasty. personal data/biological material monocentric MD Henrik Behrend Dep of Orthopaedic Surgery, KSSG KSSG, St. Gallen
Ethikkommission Ostschweiz (EKOS) 07.12.2015
2015-00040 A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled,
Multicenter Study Evaluating the Safety and Efficacy of Obeticholic Acid in
Subjects with Nonalcoholic Steatohepatitis
clinical trial drugs phase 3 multicentric C Prof. Dr. Annalisa Berzigotti Intercept Pharma Switzerland GmbH University Clinic of Visceral Surgery and Medicine, Bern
Kantonsspital St. Gallen, St. Gallen
EPATOCENTRO TICINO, Lugano
USZ, University of Zurich, Zürich
Kantonale Ethikkommission Bern Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino 01.06.2016
2015-00039 BIOTRONIK – Safety and clinical performance of the self-expanding transcatheter BIOVALVE prosthesis in subjects with severe symptomatic calcified aortic valve stenosis suitable for transfemoral transc More ... clinical trial medical devices monocentric C2 Prof. Robert Bauernschmitt BIOTRONIK AG - Clinical Affairs UniversitätsSpital Zürich - Klinik für Herz- und Gefässchirurgie, Zürich
Kantonale Ethikkommission Zürich 08.03.2016
2015-00038 Auswirkungen der Implementierung eines Gerinnungsmanagement-
Algorithmus bei herzchirurgischen Patienten – Eine Qualitätskontrolle

Impact of a coagulation management algorithm in cardiac surgery - More ...
personal data/biological material monocentric Prof. Dr. Christoph Hofer Institut für Anästhesiologie und Intensivmedizin Stadtspital Triemli Institut für Anästhesiologie und Intensivmedizin Stadtspital Triemli, Zurich
Kantonale Ethikkommission Zürich 22.12.2015
2015-00037 Predictive biomarkers of individual trajectories in elderly persons with subtle cognitive decline non clinical, involving persons monocentric A Professor Panteleimon Giannakopoulos Hôpitaux Universitaires de Genève Hôpitaux Universitaires de Genève, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 08.12.2016
2015-00035 DEVELOPMENT OF A SYSTEM TO ASSESS LOCOMOTION OF FRAIL OLDER ADULTS IN TWO DIFFERENT ENVIRONMENTS non clinical, involving persons monocentric A Dr. Amandine Dubois University of Fribourg University of Fribourg, Fribourg
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 02.02.2016 Study has ended
2015-00034 Prevalence of HPV infection using self-sampling screening and monitoring the Earlier Impact of HPV-Vaccination Program in Switzerland clinical trial medical devices monocentric A Prof Patrick Petignat Geneva university hospital Hopital universitaire de Geneve, geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 05.01.2016 Study has ended
2015-00033 A Phase I/II, multicenter, open-label, dose-escalation study of the safety and pharmacokinetics of cobimetinib in pediatric and young adult patients with previously treated solid tumors clinical trial drugs phase 1 monocentric C Dr. Nicolas Gerber F. Hoffmann-La Roche Ltd. Universitäts-Kinderspital, Zürich
Kantonale Ethikkommission Zürich 15.07.2016 yes Study has ended
2015-00032 The effect of biopolymer based lipid emulsions on GI function, GI peptide response
and satiation in healthy volunteers; a randomized, double blind, unbalanced threeway crossover study.
clinical trial other clinical trials monocentric B Dr. Andreas Setingoetter University Hospital Zurich University Hospital Zurich, Zurich
Kantonale Ethikkommission Zürich 01.04.2016 Study has ended