| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-00140 | Interaction entre les virus respiratoires communautaires et les cellules épithéliales bronchiques chez les transplantés : un élément déclencheur de l'altération chronique de la fonction pulmonaire | non clinical, involving persons | monocentric | A | Prof Caroline Tapparel Vu | Université de Genève |
Faculty of Medicine, University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 07.03.2023 | ||||||
| 2023-00139 |
Médicaments à Jour? - MaJ? Study of feasibility of a pharmaceutical service for patients with polypharmacy |
non clinical, involving persons | monocentric | A | PD Dr Jérôme Berger | Unisanté |
Unisanté, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.03.2023 | ||||||
| 2023-00138 | Bestimmung der effektiven Strahlendosis von 2 unterschiedlichen intravenös Kontrastmittel-verstärkten 18-Fluorodeoxyglucose (FDG) PET/CT Protokollen in der klinischen Routine und deren Einfluss auf di More ... | personal data/biological material | monocentric | Prof Dr med Thomas Hany | Medizinisch Radiologisches Institut |
MRI Medizinisch Radiologisches Insitut, 8001 |
Kantonale Ethikkommission Zürich | 31.03.2023 | |||||||
| 2023-00136 | A randomized, double-blind, multicenter phase III study to evaluate the long-term efficacy and safety of ABX464 25 mg or 50 mg once daily as a maintenance therapy in subjects with moderately to severe More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Benjamin Misselwitz | ABIVAX S.A. |
Inselspital Bern, Bern Intesto Gastroenterologische Praxis Crohn-Colitis-Zentrum, Bern St. Claraspital, Basel UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 17.07.2023 | yes | ||
| 2023-00135 | DOCUMENTATION OF PERIOPTIME - a cohort study | non clinical, involving persons | monocentric | A | Prof. Dr. med. Isabelle Schmitt-Opitz | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 31.03.2023 | ||||||
| 2023-00134 | Investigating TMS-induced brain plasticity –an observational 7 Tesla MRI-study | non clinical, involving persons | monocentric | A | Prof Dr. med. Tobias Bracht | University Hospital of Psychiatry and Psychotherapy |
Universitätsklinik für Psychiatrie und Psychotherapie, Bern |
Kantonale Ethikkommission Bern | 20.03.2023 | ||||||
| 2023-00133 | Objective assessment of middle- and inner-ear implants using cadaveric human temporal bones | deceased persons | monocentric | Prof. Dr. med. Alexander M. Huber |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 03.03.2023 | ||||||||
| 2023-00132 | Outcomes and predictors of complications in open thoracic and thoracoabdominal aortic repair | personal data/biological material | monocentric | Dr. med. Salome Weiss | Inselspital, Bern University Hospital |
Inselspital, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 04.05.2023 | |||||||
| 2023-00131 |
Untersuchung zur Wirkung von Monochordklängen auf die Stressregulation gesunder Erwachsener Research on the effects of monochord sounds on the stress regulation of healthy adults |
clinical trial | other clinical trials | monocentric | A | Dr. Sandra Lutz Hochreutener | ZHdK Institute for Music Research (IMR) |
Zürcher Hochschule der Künste, Zürich |
Kantonale Ethikkommission Zürich | 10.08.2023 | |||||
| 2023-00130 | Preoperative drug-resistant bacteria colonization and its impact on outcome of post-operative paediatric cardiac surgery patients. | personal data/biological material | monocentric | Vladimir Cousin |
Geneva University Hospital, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.02.2023 | ||||||||
| 2023-00128 | Sensibilisierungsmuster und Allergien auf aerogene Allergene bei Patienten mit allergischem Asthma und allergischer Rhinitis am Universitätsspital Zürich seit 2015. | personal data/biological material | monocentric | Prof. Dr. med. Marie-Charlotte Brüggen | Dermatologische Klinik |
Dermatologische Klinik, Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 17.03.2023 | Study has ended | ||||||
| 2023-00127 | A comparative assessment of Bionator and Activator appliances in the treatment of Class II malocclusion: a retrospective cohort study. | personal data/biological material | multicentric | Prof. Dr. mult. Theodore Eliades | Clinic of Orthodontics and Pediatric Dentistry, Center of Dental Medicine, University of Zurich |
Clinic of Orthodontics and Pediatric Dentistry, Center of Dental Medicine, University of Zurich, Zurich Kinder- und Jugendzahnklinik St.Gallen, St.Gallen Praxis Dr. med. dent. Tim Schröder AG, Herisau |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Ostschweiz (EKOS) | 02.02.2023 | ||||||
| 2023-00126 | Surgery for Adenocarcinoma of the Gastroesophageal Junction (GEJ) Type II: Transthoracic Esophagectomy vs. Transhiatal Extended Gastrectomy | clinical trial | other clinical trials | monocentric | A | Dr. med. Lana Fourie | University of Cologne |
Clarunis Universitäres Bauchzentrum Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.08.2023 | |||||
| 2023-00125 | Management of acute bronchitis in Switzerland with Pelargonium sidoides extract EPs 7630 versus usual care – a pragmatic, open-label, randomised controlled trial. | clinical trial | drugs | n/a | monocentric | A | Prof. Pierre-Yves Rodondi | Université de Fribourg |
University of Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.05.2023 | ||||
| 2023-00124 | EvasayilTM: A placebo-controlled trial to evaluate the efficacy and safety of spesolimab in the treatment of patients with Netherton Syndrome | clinical trial | drugs | phase 2 | monocentric | C | Dr. Lisa Weibel | Boehringer Ingelheim International GmbH |
Universitätskinderspital, Zürich |
Kantonale Ethikkommission Zürich | 18.04.2023 | yes | |||
| 2023-00123 |
Assessment of Guselkumab (Tremfya®) and IL-17 Inhibitor Therapies in Patients with Psoriatic Arthritis in Routine Clinical Practice; A Prospective, Observational Cohort Study PsABIOnd |
non clinical, involving persons | monocentric | A | Pr Jean Dudler | JANSSEN PHARMACEUTICA, NV |
HFR Fribourg -Hôpital Cantonal, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.03.2023 | ||||||
| 2023-00122 | The impact of intraoperative frozen section in patients with clinically/radiologically node-negative breast cancer (cN0/ycN0) who received neoadjuvant systemic therapy. | personal data/biological material | monocentric | Prof. Dr. med. Uwe Güth | Brust-Zentrum AG |
Brust-Zentrum Zürich AG, Zurich |
Kantonale Ethikkommission Zürich | 24.02.2023 | |||||||
| 2023-00121 | aMace - Patient-specific triflange cups in the reconstruction of severe acetabular defects – a radiological correlation between virtual planning, postoperative positioning, and bony ingrowth | non clinical, involving persons | monocentric | A | PD Dr Martin Clauss | University Hospital Basel |
University Hospital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.03.2023 | ||||||
| 2023-00118 | Preoperative localization and intraoperative detection of small parathyroid adenomas | personal data/biological material | monocentric | Dr. Henning Wolf | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.02.2023 | |||||||
| 2023-00117 | Tongue morphology and posterior airway space as predictors of response in patients with hypoglossal nerve stimulation therapy | non clinical, involving persons | multicentric | A | Prof. Dr. med. Kurt Tschopp | Kantonsspital Baselland |
Kantonsspital Baselland, Liestal Inselspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 03.05.2023 | |||||