| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01853 | Diagnostic comparability of established ultrasound and magnetic resonance techniques (elastography, multiparametric imaging) as well as immune cell profiles for non-invasive diagnosis of liver/spleen More ... | clinical trial | other clinical trials | monocentric | A | PD Dr. med. C. Jüngst | Universitätsspital Zürich |
Klinik für Gastroenterologie und Hepatologie, USZ, Zürich |
Kantonale Ethikkommission Zürich | 22.12.2023 | |||||
| 2023-01851 | Early diagnosis and aetiology of critical illness myopathy | non clinical, involving persons | monocentric | B | Prof. Dr. med. Werner Z`Graggen | Universitätskliniken für Neurochirurgie und Neurologie |
Universitätskliniken für Neurochirurgie und Neurologie, Bern |
Kantonale Ethikkommission Bern | 22.11.2023 | ||||||
| 2023-01850 | Graft Occlusion in Post-CABG Patients: A Retrospective Computed Tomography Analysis | personal data/biological material | monocentric | Denis Berdajs | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.10.2023 | |||||||
| 2023-01849 | Hip osteoarthritis aetiology: Impact of capsular stiffening on intracapsular pressure and joint loads during hip motions in a robotic ex vivo model. | deceased persons | monocentric | MD Nicolas Holzer | SWISS Foundation for Innovation and Training in Surgery (SFITS) |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 22.04.2024 | |||||||
| 2023-01848 | Reading performance with monofocal intraocular lenses | non clinical, involving persons | monocentric | A | Dr. Martin Lörtscher | Pallas Kliniken AG |
Pallas Kliniken AG, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.11.2023 | ||||||
| 2023-01846 | UTOPICA – Understanding Tonic and Phasic Irritability in help-seeking Children and Adolescents | non clinical, involving persons | multicentric | A | Sébastien Urben | CHUV - Psychiatrie |
CHUV, Lausanne University Hospital of Child and Adolescent Psychiatry and Psychotherapy Bern, Bern |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern | 23.01.2024 | yes | ||||
| 2023-01844 | Ureteral stenosis after renal transplantation: balloon dilation or surgical reconstruction. A 10 years retrospective study at the University Hospital of Zürich. | personal data/biological material | monocentric | Dr. med. Dejan Lavrek |
Klinik für Urologie, USZ, Zürich |
Kantonale Ethikkommission Zürich | 26.01.2024 | ||||||||
| 2023-01843 | Characterizing information integration in reinforcement learning: an fMRI investigation | non clinical, involving persons | monocentric | A | Prof. Dr. Maël Lebreton | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.12.2023 | ||||||
| 2023-01840 | Safety and Efficacy of Growth Friendly Instrumentation in Patients with Spinal Muscular Atrophy Type 1 in the Disease-Modifying Treatment Era | personal data/biological material | monocentric | PD Dr. med. Daniel Studer | Children's Hospital, University of Basel |
Children's Hospital, University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.10.2023 | |||||||
| 2023-01839 | Characterization of heart rate variability using the Bora Band® | non clinical, involving persons | monocentric | A | PD Qian Zhou | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.11.2023 | ||||||
| 2023-01837 | Häufigkeit und Ursachen von wiederholten Hospitalisationen von Kindern mit Trachealkanüle: Eine quantitative retrospektive Querschnittstudie | personal data/biological material | monocentric | Dr. Brigitte Seliner | Universitäts Kinderspital Zürich |
Universitäts Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 01.12.2023 | |||||||
| 2023-01835 | Le syndrome de la porte tournante en psychiatrie : le point de vue du patient. Une étude qualitative | non clinical, involving persons | monocentric | A | M. Patrick Martino | CHUV - Hôpital Cery |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.11.2023 | ||||||
| 2023-01834 | Association of the fecal microbiota with cognitive delay in children from Madagascar (AfriGutBrain) | personal data/biological material | monocentric | Prof. Pascale Vonaesch | UNIL - FBM - DMF - 2310.1 |
University of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.10.2023 | |||||||
| 2023-01833 | Conebeam CT-based online Adaptive Radio-Therapy for Esophageal Cancer (ARTEC) | non clinical, involving persons | monocentric | A | MD Hossein Hemmatazad | INSELSPITAL, Universitätsklinik Bern |
INSELSPITAL, Universitätsklinik Bern Universitätsklinik für Radio-Onkologie, Bern |
Kantonale Ethikkommission Bern | 05.02.2024 | ||||||
| 2023-01832 | A 5-year observational study to investigate the use of vocal biomarkers in people with Multiple Sclerosis | non clinical, involving persons | monocentric | A | Dr. med. Helly Hammer | Inselspital |
Inselgruppe, Bern |
Kantonale Ethikkommission Bern | 16.01.2024 | ||||||
| 2023-01830 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects with Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH) and Fibrosis | clinical trial | combination drugs/devices | phase 3 | multicentric | C | Prof. Jean-Francois Dufour | Akero Therapeutics, Inc. |
Centre des Maladies Digestives Lausanne, Lausanne Inselspital Universitätsspital Bern, Department of Visceral Surgery and Medicine, Bern Kantonsspital Olten, Olten Kantonsspital St. Gallen, St. Gallen |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 21.03.2024 | |||
| 2023-01829 | Synchrony Real world - A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects with Non-Invasively Diagnosed Nonalcoholic steatohep More ... | clinical trial | combination drugs/devices | phase 3 | multicentric | C | Prof. Dr. med. Jean-Francois Dufour | Akero Therapeutics, Inc. |
Centre des Maladies Digestives Lausanne, Lausanne Inselspital Universitätsspital Bern, Department of Visceral Surgery and Medicine, Bern Kantonsspital Olten, Olten Kantonsspital St.Gallen, Klinik für More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 21.03.2024 | |||
| 2023-01828 | Limitation of Therapeutic effort in Internal Medicine | personal data/biological material | monocentric | Dr Malik Benmachiche | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 22.01.2024 | |||||||
| 2023-01827 | M16-194: A Phase 3, Multi-Center Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Risankizumab with Open-Label Induction, Randomized Double-Blind Maintenance, and Long-Term Extension Pe More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Carsten Posovsky | AbbVie Inc. |
Universitätskinderspital Zürich, Zürich Inselspital, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 13.02.2024 | yes | ||
| 2023-01826 | Modeling of proton RBE variations in skull base and head and neck cancer patients treated with Pencil Beam Scanning Proton Therapy | personal data/biological material | monocentric | Dr. Giovanni Fattori | Center for Proton Therapy at Paul Scherrer Institut |
Center for Proton Therapy at Paul Scherrer Institut, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.11.2023 | |||||||