| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-01704 | New therapeutical targets in conjunctival melanoma | personal data/biological material | monocentric | Dr Alexandre Moulin | Hôpital ophtalmique Jules-Gonin |
Jules-Gonin Eye Hospital, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.08.2023 | |||||||
| 2022-01702 | Comparison of the effects of SGLT2 inhibitors, statins and absence of hypolipidemic drugs on atherosclerotic plaque progression and repercussions on cardiovascular disease risk | personal data/biological material | monocentric | Prof. Dr. med. Andreas Christe | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 10.01.2023 | |||||||
| 2022-01701 | GS-US-611-6273: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GS-5245 for the Treatment of COVID-19 in Participants With High-Risk for Disease Pr More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. / Alexandra / Calmy | Gilead Sciences, Inc. |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.02.2023 | Study has ended | |||
| 2022-01699 | Acoustic emission biomarkers for the detection and monitoring of early knee osteoarthritis | non clinical, involving persons | monocentric | A | Dr. Vincent Stadelmann | ETH Lausanne |
Schulthess Klinik, Zürich |
Kantonale Ethikkommission Zürich | 11.11.2022 | ||||||
| 2022-01698 | A Phase 2/3, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group, 2-Arm, Multicenter, Operationally Seamless Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacodynamics, Pharmaco More ... | clinical trial | drugs | phase 2 | monocentric | C | Dr. med. Paolo Ripellino | argenx BV |
Ospedale Regionale di Lugano, Lugano |
Comitato etico cantonale Ticino | 04.04.2023 | ||||
| 2022-01697 | Monitoring of melanoma patients using Oncobit™ PM | non clinical, involving persons | monocentric | A | Dr. Egle Ramelyte | Oncobit AG |
University Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 11.11.2022 | ||||||
| 2022-01696 | Deep learning-based Ultrafast Ultrasound Image Reconstruction | non clinical, involving persons | monocentric | A | Prof. Jean-Philippe Thiran | EPFL - STI - IEL - LTS 5 |
EPFL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.12.2022 | ||||||
| 2022-01695 | Introducing minimally invasive liver surgery in a tertiary center of Southern Switzerland | personal data/biological material | monocentric | Dr.med Alessandra Cristaudi | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 29.11.2022 | Study has ended | ||||||
| 2022-01694 | Correlation between basketball match participation and eccentric hamstrings muscle fatigue in men and women. A pilot study. | non clinical, involving persons | monocentric | A | PT Sebastiano Nutarelli | EOC |
EOC - Servizio di Ortopedia e Traumatologia, Lugano |
Comitato etico cantonale Ticino | 31.01.2023 | yes | |||||
| 2022-01693 | FENTALOGS - Analysis of hair samples for their opioid content | non clinical, involving persons | multicentric | A | Tina Maria Binz | Universität Zürich |
Universtität Zürich, Zürich Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 18.11.2022 | yes | ||||
| 2022-01692 | Integrating hospital data for monitoring the SARS-CoV-2 epidemic in near real-time | personal data/biological material | monocentric | Guido Beldi | Institute of Social and Preventive Medicine (ISPM) |
Inselgruppe AG, Bern |
Kantonale Ethikkommission Bern | 11.10.2022 | |||||||
| 2022-01691 | Structured shared decision making for patients undergoing elective surgical or transcatheter aortic valve replacement (TOGETHER): A randomized-controlled trial | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Thomas Pilgrim | Insel Gruppe AG |
Insel Gruppe AG, 3010 Bern |
Kantonale Ethikkommission Bern | 03.02.2023 | |||||
| 2022-01688 | Extracellular Vesicle Surface Markers In Acute Cerebrovascular Syndromes | non clinical, involving persons | monocentric | A | PD Dr Med Carlo Cereda | Stroke Center, Neurocenter of Southern Switzerland |
Stroke Center, Neurocenter of Southern Switzerland, Lugano |
Comitato etico cantonale Ticino | 18.11.2022 | ||||||
| 2022-01687 | A Phase I/II study of brigatinib in pediatric and young adult patients with ALK+ Anaplastic Large Cell Lymphoma, Inflammatory Myofibroblastic Tumors or other solid tumors - the BrigaPED study | clinical trial | drugs | phase 1/2 | monocentric | C | Dr. med. / Manuel / Diezi | Princess Máxima Center for Pediatric Oncology |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.03.2023 | yes | |||
| 2022-01686 | A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC and Lenalidomide (Tec-DR) and Talquetamab in Combination with Daratumumab SC and Lenalidomide (Tal-DR) versus Daratu More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Michael Baumann | Janssen-Cilag International N.V. |
Kantonsspital St. Gallen, St. Gallen Inselspital Bern, Bern |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Bern | 06.07.2023 | |||
| 2022-01684 | Anhydroglucitol as a measure of the functional beta-cell mass in children with type 1 diabetes – pilot study | non clinical, involving persons | monocentric | A | Dr. Philippe Klee | University Hospitals of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 31.10.2022 | yes | |||||
| 2022-01682 | Gastric point-of-care sonography with focus on gastric emptying time in patients with traumatic injuries. A prospective observational study | non clinical, involving persons | monocentric | A | Dr. med. Roman Meierhans | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 28.10.2022 | ||||||
| 2022-01681 | Investigator-initiierte, retrospektive, single-center Studie zur Entwicklung eines Frühwarnsystems für das Erkennen einer Verschlechterung von Patienten eines Akutspitals | personal data/biological material | monocentric | Prof. Dr. med. Jens Eckstein | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.10.2022 | |||||||
| 2022-01679 | International, multicenter, prospective registry to collect data on patients undergoing segmental mandibular defect reconstruction (SMDR) following oral squamous cell carcinoma (OSCC) resection | non clinical, involving persons | monocentric | A | PD Dr. Florian Thieringer | AO Foundation |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.11.2022 | ||||||
| 2022-01678 | Swiss Personalized Oncology National Data Stream (SPO-NDS) – In-depth tumor profiling in patients with advanced malignancies | non clinical, involving persons | multicentric | A | Prof. Dr. Andreas Wicki | Department of Medical Oncology and Haematology Clinic of the University of Zurich |
University Hospital Zürich, Zürich Inselspital Bern, Bern Universitätsspital Basel, Basel Kantonsspital Baselland, Liestal Hôpiteaux Universitaires Genève HUG, Genève Centre Hospitalier Universitaire More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 10.08.2023 | |||||