| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-00395 | Optimizing resection margins of Ewings- and Osteosarcoma through improved MRI targeting. | personal data/biological material | multicentric | Professor Andreas H. Krieg | Universitäts-Kinderspital beider Basel (UKBB) |
Universitäts-Kinderspital beider Basel UKBB, Basel Inselspital, Universitätsspital Bern, Bern Universitätsklinik Balgrist, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 12.07.2023 | ||||||
| 2023-00394 | A Phase 3, Open-label Study Evaluating the Long‑term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor Triple Combination Therapy in Cystic Fibrosis Subjects 1 Year of Age and Older | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. Alexander Möller | Vertex Pharmaceuticals Germany GmbH |
Universitäts-Kinderspital, Zürich Inselspital, Kinderklinik, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 20.06.2023 | yes | ||
| 2023-00393 | Minimally invasive replacement of aortic root, ascending aorta and hemiarch via partial upper sternotomy: a propensity-score matched comparison with full sternotomy | personal data/biological material | monocentric | Prof. Dr. med. Dr. h. c. Omer Dzemali |
Klinik für Herzchirurgie, Stadtspital Triemli Zürich, Zürich |
Kantonale Ethikkommission Zürich | 05.09.2023 | ||||||||
| 2023-00392 | A pilot study on the influence of temporo-occipital transcranial magnetic brain stimulation on aversive episodic memory performance | clinical trial | other clinical trials | monocentric | A | Dr. Ehssan Amini | Universität Basel |
University of Basel, Division of Cognitive Neurosience, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.04.2023 | |||||
| 2023-00391 | Health related quality of life in egg white allergy | non clinical, involving persons | monocentric | A | Prof. Dr. med. Peter Schmid-Grendelmeier | University of Zurich, University hospital of Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 18.07.2023 | ||||||
| 2023-00390 | Retrospective international multicenter study to validate the Iwate and Institut Mutualiste Montsouris difficulty scoring systems and to develop a novel scoring system for laparoscopic and robotic liv More ... | personal data/biological material | monocentric | Dr Gaëtan-Romain Joliat | Singapore General Hospital |
Centre hospitalier universitaire vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.06.2023 | Study has ended | ||||||
| 2023-00389 | Kniegelenksnahe Osteotomien – Eine retrospektive Datenanalyse | personal data/biological material | monocentric | Prof. Dr. Sandro Fucentese | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 14.04.2023 | |||||||
| 2023-00388 | Painless Sharp Wound Debridement with Lidocaine-23%-Tetracaine-7% Gel versus EMLA 5% Cream: a single-blind, crossover, randomised, controlled trial | clinical trial | drugs | phase 2 | monocentric | C | Prof. Dr. med. Jürg Hafner |
Dermatologische Klinik USZ, Zürich |
Kantonale Ethikkommission Zürich | 28.03.2023 | |||||
| 2023-00387 | Association between coraco-glenoid ligament anatomical variants and SLAP lesion. A magnetic resonance arthrography study. | personal data/biological material | monocentric | PD Dr. Filippo Del Grande | EOC Ospedale Regionale di Lugano - Civico |
Clinica EOC IIMSI, Lugano |
Comitato etico cantonale Ticino | 26.04.2023 | |||||||
| 2023-00386 | Evolution au long cours des dérivations du canal pancréatique par voie endoscopique | personal data/biological material | monocentric | Dr Sébastien Godat | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.09.2023 | |||||||
| 2023-00385 | A Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-861 for the Treatment of Narcolepsy Without Cataplexy (Narcolepsy Type 2) | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Dr. med. Ramin J.Khatami | Takeda Development Center Americas, Inc. |
Center for Sleep Research and Sleep Medicine, Clinic - Barmelweid AG, Switzerland, Barmelweid Department of Neurology Schlaf-Wach-Epilepsie Zentrum Inselspital, Bern University Hospital, University of More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino | 17.05.2023 | Study has ended | ||
| 2023-00384 | Determinanten des Belastungsempfindens an der aeroben und anaeroben Schwelle von Patienten in stationärer psychosomatischer Behandlung | personal data/biological material | monocentric | Dr. sc. med. Gavin Brupbacher | Oberwaid AG |
Oberwaid AG, St.Gallen |
Ethikkommission Ostschweiz (EKOS) | 02.03.2023 | |||||||
| 2023-00383 |
Menthacarin in the treatment of functional gastrointestinal disorders A multi-centre, multi-national, single-arm, phase IV clinical trial |
clinical trial | drugs | phase 4 | multicentric | A | Prof. Dr. med. Stephan Vavricka | Dr. Willmar Schwabe GmbH & Co. KG |
Zentrum für Gastroenterologie und Hepatologie, Zürich Gastroenterologische Gruppenpraxis GGP, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 06.06.2023 | Study has ended | ||
| 2023-00382 | An open-label, nonrandomized, multicenter extension study to evaluate the long-term safety and efficacy of pegcetacoplan in participants with C3 glomerulopathy or immune-complex membranoproliferative More ... | clinical trial | combination drugs/devices | phase 3 | monocentric | C | FADI FAKHOURI | Apellis Pharmaceuticals, Inc. |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 04.09.2023 | yes | |||
| 2023-00381 | Feasibility of blinding spinal manual therapy interventions for a trial assessing management of primary care patients with back pain: the SALuBRITY blinding feasibility randomised controlled trial | clinical trial | other clinical trials | monocentric | A | Dr / Cesar / Hincapié | Balgrist University Hospital and University of Zurich |
Balgrist University Hospital, Zurich |
Kantonale Ethikkommission Zürich | 11.04.2023 | |||||
| 2023-00380 | Accompagnement spirituel STIV-RePer : le vécu des patient-e-s et le processus décisionnel des accompagnant-e-s | non clinical, involving persons | monocentric | A | PhD, Grégory Dessart | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.08.2023 | ||||||
| 2023-00379 | Offene versus laparoskopisch roboter-assistierte Ureterozystoneostomie bei distaler Harnleiterstenose oder -verletzung | personal data/biological material | monocentric | Prof. Dr. med. Hubert John | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 12.05.2023 | |||||||
| 2023-00377 | Postoperative outcomes after elective anatomical and extraanatomical lung resections in patients with a history of COVID-19 | personal data/biological material | monocentric | Dr. Michail Galanis | Inselspital/Klinik für Thoraxchirurgie |
Inselspital/Klinik für Thoraxchirurgie, Bern |
Kantonale Ethikkommission Bern | 03.05.2023 | |||||||
| 2023-00375 | Klinisch und radiologisches Ergebnisse zehn Jahre nach Implantation eines unzementierten Kurzschaftes in der Hüftprothetik | personal data/biological material | monocentric | Prof. Dr. med. Näder Helmy | Bürgerspital Solothurn |
Klinik für Orthopädie und Traumatologie, Bürgerspital Solothurn, Solothurn |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.07.2023 | |||||||
| 2023-00373 |
CONTINUOUS VERSUS INTERMITTENT INFUSION OF VANCOMYCIN: A GAME CHANGER IN CRITICALLY ILL PATIENTS? |
personal data/biological material | monocentric | Prof. Dr. med. Barbara Hasse | Universitätsspital Zurich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 02.06.2023 | |||||||