| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-00638 | Aortic Valve Replacment: Partial Upper Sternotomy versus right antero-lateral Thoracotomy. A propensity Score Matched Analysis | personal data/biological material | monocentric | Prof. Dr. med. Dr. h.c. Omer Dzemali |
Klinik für Herzchirurgie Stadtspital Zürich Triemli, Zürich |
Kantonale Ethikkommission Zürich | 23.05.2023 | ||||||||
| 2023-00636 | The different diagnostic values of polysomnographies at low and at moderate altitude - A randomized crossover trial | clinical trial | other clinical trials | monocentric | A | PD Dr. med./ Tsogyal/ Latshang |
Kantonsspital Graubünden, Chur |
Kantonale Ethikkommission Zürich | 26.05.2023 | ||||||
| 2023-00635 | The effects of GLP-1-RAs in adolescents with obesity, complicated with NAFLD | non clinical, involving persons | monocentric | A | Dr. Maria-Christina Antoniou | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.08.2023 | yes | |||||
| 2023-00634 | Development and validation of artificial intelligence for acute kidney injury prediction | personal data/biological material | monocentric | Professor Sophie de Seigneux | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.06.2023 | |||||||
| 2023-00633 | Évaluation des compétences socio-émotionnelles chez les enfants et les adolescents avec déficience visuelle (DEVI-CSE) | non clinical, involving persons | monocentric | A | Nicolas Ruffieux | UNIFR |
Université de Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.07.2023 | yes | |||||
| 2023-00632 | Comparing Standard of Care Versus Apixaban in patients with a Ventricular Assist Device: a Parallel, randomised, non-inferiority, open label, control, pilot-study, The Apixi-VAD trial | clinical trial | drugs | phase 3 | monocentric | B | Dr. med. Bruno Schnegg | St Vincent's Hospital Sydney Limited |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 06.10.2023 | ||||
| 2023-00631 | Assessment of cancer survivors to understand tumor control through checkpoint inhibitor therapy | non clinical, involving persons | monocentric | A | Prof. Dr. Lukas Flatz | Labor Dr. Risch AG |
Labor Dr. Risch AG, Buchs SG |
Ethikkommission Ostschweiz (EKOS) | 04.05.2023 | ||||||
| 2023-00630 | Reducing stress and elevating resilience in refugee aid workers | clinical trial | other clinical trials | monocentric | A | Dr. med. Anne Jachmann | Swiss Tropical and Public Health Institute |
Swiss Tropical and Public Health Institute, Allschwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.07.2023 | |||||
| 2023-00629 | Preoperative thermographic detection of perforating vessels in DIEP-flaps | personal data/biological material | monocentric | Prof. Dr.med Yves Harder | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 16.06.2023 | Study has ended | ||||||
| 2023-00627 | Low-dose tin-prefiltered photon-counting vs. full-dose energy integrating computed tomography of the lumbar spine: Balancing image quality and radiation dose | personal data/biological material | monocentric | Prof. Dr. med. Reto Sutter | University Hospital Balgrist |
University Hospital Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 09.05.2023 | |||||||
| 2023-00626 | Patients with pre-existing psychiatric disorders treated on the intensive care unit: A retrospective, single-centre cohort study | personal data/biological material | monocentric | Dr Med Francesca Porta | Intensive Care Unit |
Intensive Care Unit, Kantonspital Graubünden, Chur |
Kantonale Ethikkommission Zürich | 20.06.2023 | |||||||
| 2023-00625 | Validazione del Cranio Cervical Flexion Test (CCFT) utilizzando una strumentazione digitale. | non clinical, involving persons | monocentric | A | Prof Marco Barbero | Laboratorio di Ricerca in Riabilitazione, DEASS, SUPSI |
Laboratorio di Ricerca in Riabilitazione, DEASS, SUPSI, Manno |
Comitato etico cantonale Ticino | 21.06.2023 | ||||||
| 2023-00624 | Randomised, double-blind, placebo-controlled, Phase IIb/Phase III study to evaluate the efficacy and safety of spesolimab in patients with moderate to severe hidradenitis suppurativa. Lunsayil 1. | clinical trial | drugs | phase 2 | multicentric | C | Professor Alexander Navarini | Boheringer Ingelheim International GmbH |
University Hospital of Basel, Basel University of Bern Inselspital, Bern University Hospital of Geneve, Geneve University Hospital Zurich, Zurich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 08.06.2023 | Study has ended | ||
| 2023-00623 | Invasive Group A Streptococcus (iGAS) infection in adult population in Switzerland. A multicenter retrospective analysis | personal data/biological material | multicentric | Pr Jacques Schrenzel | HUG |
HUG, Geneva Institut for Infectious Diseases, Bern Hirslanden Klinik St Anna, Luzern University hospital of Basel, Basel HUG, GENEVA Cantonal Hospital of St Gallen, St Gallen Spital Thurgau AG, Thurga More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 04.12.2023 | ||||||
| 2023-00620 | A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, for Stroke Prevention after an Acute Is More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof.Dr.med. Mira Katan Kahles | Janssen-Cilag International NV |
Universitätsspital Basel, Basel Inselspital Bern, Bern Kantonsspital Aarau, Aarau Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 12.09.2023 | |||
| 2023-00619 | Quantitative analysis of facial asymmetry based on three-dimensional photography: a longitudinal observation of a cohort with juvenile idiopathic arthritis. | personal data/biological material | monocentric | PD Dr. Dr. Raphael Patcas | University of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 12.06.2023 | |||||||
| 2023-00618 | BIOEQUIVALENCE OF NEBIVOLOL AND RAMIPRIL FOLLOWING THEIR ORAL CO-ADMINISTRATION AS FIXED AND EXTEMPORANEOUS COMBINATION IN HEALTHY SUBJECTS | clinical trial | drugs | phase 1 | monocentric | C | Dr Milko Radicioni | MENARINI RICERCHE S.p.A. |
CROSS Research S.A. Phase I Unit, Arzo, Switzerland |
Comitato etico cantonale Ticino | 02.06.2023 | Study has ended | |||
| 2023-00617 | Single center retrospective study: Neonatal complex arch reconstruction using ducal patency for lower body perfusion: Long-term growth and function. Patient Cohort treated at Kinderspital Zürich durin More ... | personal data/biological material | monocentric | Prof. Dr. med. Hitendu Dave | Herzchirurgie |
Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 30.08.2024 | |||||||
| 2023-00616 | A PHASE Ib/II, OPEN-LABEL, MULTICENTER, RANDOMIZED UMBRELLA STUDY EVALUATING THE EFFICACY AND SAFETY OF MULTIPLE TREATMENT COMBINATIONS IN PATIENTS WITH LOCALLY ADVANCED SQUAMOUS CELL CARCINOMA OF THE More ... | clinical trial | combination drugs/devices | phase 1/2 | multicentric | C | Prof. Dr. med. Anja Lorch | F. Hoffmann-La Roche Ltd |
Klinik für Medizinische Onkologie und Hämatologie,Universitätsspital Zürich, Zürich Universitätsklinik für Medizinische Onkologie, Inselspital, Bern Kantonsspital Graubünden, Onkologie/Hämatologie, Ch More ... |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 26.06.2023 | Study has ended | ||
| 2023-00615 | MAMA–CF – Monitoring Airway Measures in Cystic Fibrosis | non clinical, involving persons | monocentric | A | PD Dr Dr Jakob Usemann | Kinderspital Zürich |
Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 09.06.2023 | yes | |||||