| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00196 | CLOU064J12301 - A randomized, double-blind, double-dummy, placebocontrolled, multicenter, Phase 3 study assessing the efficacy, safety, and tolerability of 2 doses of remibrutinib over a 68-week treat More ... | clinical trial | drugs | phase 3 | multicentric | C | PD. Dr. Dr. Morteza Jafari | Novartis Pharma Schweiz AG |
Inselspital/ Universitätsklinik für Dermatologie, Bern Universitätsspital Basel, Dermatologie, Basel University Hospital Zurich Clinic for Dermatology, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 23.07.2025 | |||
| 2025-00195 | Complexity adjusted learning curve assessment by multiple endpoints in laparoscopic and robotic liver resections: a retrospective study | personal data/biological material | monocentric | Dr. med Alessandra Cristaudi | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 20.02.2025 | |||||||
| 2025-00194 | REAL WORLD UTILIZATION AND EFFECTIVENESS OF CAMZYOS® (MAVACAMTEN) IN PATIENTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (OHCM) IN SWITZERLAND | personal data/biological material | multicentric | PD Dr. med. Christiane Gruner | Bristol-Myers Squibb SA |
Department of Cardiology - University Hospital Zurich, Zürich Cantonal Hospital of Luzern, Luzern University Hospital Basel, Basel Lausanne University Hospital (CHUV), Lausanne |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.07.2025 | ||||||
| 2025-00193 | Should prophylactic partial arch replacement be standard in elective valve-sparing root replacement? A retrospective study on the outcomes of concomitant partial arch replacement | personal data/biological material | monocentric | Prof. Dr. med. Florian Schoenhoff | Department of Cardiac Surgery |
Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 24.02.2025 | |||||||
| 2025-00192 | Apport du séquençage à haut débit (NGS) et de l’hybridation in situ fluorescente (FISH) pour la caractérisation des néoplasies hématologiques : cartographie génétique en vie réelle, contribution diagn More ... | personal data/biological material | monocentric | Prof. Laurence de Leval | CHUV |
CHUV/IPA, LAUSANNE |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.06.2025 | |||||||
| 2025-00191 | PRODATA - Epidémiologie et facteurs PROnostiques de la Dissection Aortique de Type A | personal data/biological material | monocentric | Pr Lucas Liaudet | CHUV - SMIA |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.04.2025 | |||||||
| 2025-00190 | Non-invasive transcutaneous vagus nerve stimulation (tVNS) in acute stroke neurorehabilitation: Enhancing Motor Recovery and Cortical Repair | clinical trial | other clinical trials | monocentric | B | Prof. Simon Jung | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 04.08.2025 | |||||
| 2025-00189 | The role of Neuromonitoring in patients with acute brain injuries to assess the interplay between brain and other organ system in different systemic conditions. | personal data/biological material | monocentric | PD Dr. med. Giovanna Brandi | Institute of Intensive Care Medicine, Zurich University Hospital |
Institute for Intensive Care Medicine, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 15.07.2025 | |||||||
| 2025-00186 | Reward-Stress Interactions as Neural Substrate for Resilience and Vulnerability in Mental Health after Early Life Stress | non clinical, involving persons | monocentric | A | Prof. Dr. Chantal Martin Sölch | University of Fribourg |
University of Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.06.2025 | ||||||
| 2025-00184 | AFFIRM: A Randomized, Double-Blind, Placebo-Controlled, Study to Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients with Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Andreas Kremer | Gilead Sciences, Inc. |
USZ, Zürich |
Kantonale Ethikkommission Zürich | 13.06.2025 | ||||
| 2025-00183 | The Influence of Systemic Conditions on the Prevalence of Peri-Implant Diseases: A Cross-Sectional Study | personal data/biological material | monocentric | Dr. Clemens Raabe | Klinik für Oralchirurgie und Stomatologie |
Klinik für Oralchirurgie und Stomatologie, zmk Bern, Bern |
Kantonale Ethikkommission Bern | 04.03.2025 | |||||||
| 2025-00182 | International Registry for CAncer-related STroke Research: The I-CAST Registry | personal data/biological material | multicentric | Prof Simon Jung |
Department of Neurology, University Hospital of Bern, Switzerland, Bern Department of Neurology, University Hospital of Lausanne, Lausanne |
Kantonale Ethikkommission Bern | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.09.2025 | |||||||
| 2025-00181 | COMPANION DIAGNOSTIC - A Phase 3, Open-label, Multicenter, Randomized Trial of Trastuzumab Deruxtecan with Bevacizumab Versus Bevacizumab Monotherapy as First-line Maintenance Therapy in HER2-Expressi More ... | personal data/biological material | monocentric | Erwan Gouranton | Daiichi Sankyo, Inc |
Labcorp, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 10.04.2025 | |||||||
| 2025-00179 | Prevalence and Clinical Significance of Thyroid Incidentalomas in PSMA hybrid PET: a single institution retrospective study | personal data/biological material | monocentric | PD Dr. med. Gregoire Morand | Otorhinolaryngology |
USZ Klinik für Ohren-, Nasen-, Hals- und Gesichtschirurgie, Zürich |
Kantonale Ethikkommission Zürich | 16.05.2025 | |||||||
| 2025-00178 | Comparing Scheimpflug and OCT Imaging to assess the need for Re-Cross-Linking: A Retrospective Quality Assessment | personal data/biological material | monocentric | Professor Farhad Hafezi |
ELZA Institute AG, Dietikon |
Kantonale Ethikkommission Zürich | 10.06.2025 | ||||||||
| 2025-00177 | Physical activity in hospitalized patients: a prospective cohort study | non clinical, involving persons | monocentric | A | Ms Manuela Rohner-Spengler | Luzerner Kantonsspital Luzern |
Luzerner Kantonsspital, 6000 Luzern 16 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.02.2025 | ||||||
| 2025-00176 |
MorningLyte A Phase III randomized, open-label, international, multicenter study evaluating the efficacy and safety of mosunetuzumab plus lenalidomide in comparison to anti-CD20 monoclonal antibody p More ... |
clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Carmen de Ramon Ortiz | LYSARC-The Lymphoma Academic Research Organization |
Hôpitaux universitaires de Genève, Service d'hématologie, Genève Spital STS AG, Thun Kantonsspital Baselland, Liestal Kantonsspital Olten, Olten Ente Ospedaliero Cantonale IOSI, Bellinzona Hôpital Can More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 23.04.2025 | |||
| 2025-00175 | Precision Sleep Medicine: Hardware and Software Innovations for the Combined Diagnosis and Treatment of Sleep Apnea at the Point-of-Care. | personal data/biological material | multicentric | Dr. med. Matthias Herrmann | Universitätsspital Basel |
Universitätsspital Basel, Basel Universitäts-Kinderspital beider Basel (UKBB), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.03.2025 | ||||||
| 2025-00174 | Reliability of the Coronal Plane Alignment of the Knee classification | personal data/biological material | monocentric | Dr. Hermes Miozzari | Hôpitaux Universitaires de Genève - Service de Chirurgie Orthopédique et traumatologie de l'appareil moteur |
Hôpitaux Universitaires de Genève Service de Chirurgie Orthopédique et Traumatologie de l’appareil moteur, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.03.2025 | |||||||
| 2025-00172 | Spatial proteomics of the human spinal cord after an injury. | personal data/biological material | monocentric | Prof. Claudia Kathe | UNIL - FBM - DNF - Général |
Department of Fundamental Neurosciences, University of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.06.2025 | |||||||