| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-01375 |
Malattia delle piccole vie aeree e complicanze dopo resezione polmonare (Small Airways Dysfunction and complications after lung resection) |
personal data/biological material | monocentric | PD, MD Miriam Patella | Ospedale San Giovanni, EOC |
Reparto di Chirurgia Toracica, Ente Ospedaliero Cantonale, Bellinzona |
Comitato etico cantonale Ticino | 23.08.2024 | |||||||
| 2024-01374 | Florid and pleomorphic lobular carcinoma in situ of the breast: towards an increasingly uniform management. A multicenter observational retrospective study | personal data/biological material | monocentric | Prof. Mathias Fehr | Spital Thurgau AG |
Frauenklinik Spital Thurgau AG, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 11.07.2024 | |||||||
| 2024-01373 | Dixon-based MRI: Triceps surae muscle volume and intramuscular fat in Achilles tendinopathy | personal data/biological material | monocentric | Prof. Dr. med. Reto Sutter | Balgrist University Hospital |
Balgrist University Hospital, Zürich |
Kantonale Ethikkommission Zürich | 20.08.2024 | |||||||
| 2024-01371 | Does the Core Yellow Flag Index (CYFI) correlate with chronic pain after surgery in patients undergoing spinal surgery? | non clinical, involving persons | monocentric | A | Dr. med. Christine Pietsch | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 18.07.2024 | ||||||
| 2024-01370 | Autophagy in human myocardium with ischemia and infarction | personal data/biological material | monocentric | Prof. Dre méd. Sara Sabatasso |
Centre universitaire romand de Médecine légale (CURML), Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.05.2025 | ||||||||
| 2024-01369 | Effect of controlled hypotension on neurocognition in patients undergoing shoulder arthroscopies in beach chair position, a Randomized Clinical Trial | clinical trial | other clinical trials | monocentric | A | Dr. phil. Wilhelms Schellekens | Department of Anesthesiology, KSA |
KSA, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.09.2024 | |||||
| 2024-01368 | Funktionelle Knie-Assessments im Exergaming: Welche Variablen der Biomechanik bilden die Basis für das physiotherapeutische Rating? | non clinical, involving persons | monocentric | A | Michelle Haas | ZHAW - Zürcher Hochschule für angewandte Wissenschaften, Departement Gesundheit |
ZHAW Departement Gesundheit, Winterthur |
Kantonale Ethikkommission Zürich | 27.09.2024 | Study has ended | |||||
| 2024-01367 | SHuNo-Influence of body position on shoulder strength measurements with the Humac Norm dynamometer and its association with shoulder muscle activity | non clinical, involving persons | monocentric | A | Prof. Dr. Annegret Mündermann | University of Basel |
Department of Biomedical Engineering, University of Basel, Allschwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.08.2024 | Study has ended | |||||
| 2024-01366 | A Phase I/II trial to assess the safety, tolerability and preliminary anti-tumour activity of oral combination antibiotic therapy to modulate the microbiome in combination with enzalutamide in patient More ... | clinical trial | drugs | phase 1/2 | monocentric | C | Dr. Ilaria Colombo | The Institute of Cancer Research and Royal Marsden NHS Foundation Trust |
IOSI, Bellinzona |
Comitato etico cantonale Ticino | 11.11.2024 | ||||
| 2024-01365 | Implementing second trimester uterine artery doppler using uterine artery score in routine prenatal care | non clinical, involving persons | monocentric | A | Dr. Sara Ardabili | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.07.2024 | ||||||
| 2024-01363 | Comparison of efficacy of ibuprofen versus diclofenac in preventing premature ovulation in natural IVF cycles | personal data/biological material | monocentric | Prof. Dr. med. Michael von Wolff | Insel Gruppe AG und University of Berne |
Gynaecological Endocrinology and Reproductive Medicine University Women’s Hospital, Insel Gruppe AG und University of Berne, Berne |
Kantonale Ethikkommission Bern | 29.11.2024 | |||||||
| 2024-01362 | Pancreatic adenosquamous carcinoma: a single center retrospective study | personal data/biological material | monocentric | Dr Shu Sasaki | CHUV - Chirurgie viscérale |
Centre hospitalier universitaire vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.07.2024 | Study has ended | ||||||
| 2024-01361 | Development and validation of a standardized assessment instrument for health-related quality of life (HrQoL) in patients with classical homocystinuria | non clinical, involving persons | monocentric | A | Prof. Dr. Martina Huemer | Kinderspital Zürich |
Kinderspital Zürich, 8032 Zürich |
Kantonale Ethikkommission Zürich | 27.09.2024 | yes | |||||
| 2024-01360 |
Evaluation of the use and clinical relevance of stool multiplex PCR analyses at the University Hospital Basel |
personal data/biological material | monocentric | Prof. Dr. med. Michael Osthoff | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.07.2024 | |||||||
| 2024-01358 | An open-label, multicenter, randomized Phase 2 study of the ATR inhibitor tuvusertib in combination with the PARP inhibitor niraparib or the ATM inhibitor lartesertib in participants with BRCA mutant More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Jens Huober | Merck Healthcare KGaA |
Kantonsspital St. Gallen, St. Gallen Kantonsspital Baselland, Liestal Spital Thurgau, Frauenfeld Ente Ospedaliero Cantonale ( EOC ) Istituto Oncologico della Svizzera Italiana (IOSI) Ospedale San Giov More ... |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 29.08.2024 | Study has ended | ||
| 2024-01357 | TRI0376 - RHH646A02101 Biomarker Assay Development | personal data/biological material | monocentric | Didier Laurent, PhD | Novartis Pharma AG - Biomedical Research |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.07.2024 | |||||||
| 2024-01356 | Consolidation therapy with immune reconstitution therapy (cladribine) in relapsing multiple sclerosis patients following a treatment with anti-CD20 compounds: a pivotal study | non clinical, involving persons | multicentric | A | Prof. Dr. med Chiara Zecca | Ospedale Regionale di Lugano, Neurocenter of Southern Switzerland |
Ospedale Regionale di Lugano, Neurocenter of Southern Switzerland, Via Tesserete 46, 6900 Lugano Universitaetsklinik fur Neurologie – Inselspital, Bern Luzerner Kantonspital, Luzern CHUV Centre hospit More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.09.2024 | |||||
| 2024-01354 | Measurement Properties (Reliability and Validity) of a Set of Assessments evaluating Physical Function in People with Hemophilia | clinical trial | other clinical trials | monocentric | A | Dr. Rudolf Knols | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 31.10.2024 | |||||
| 2024-01353 |
Micro-clots and neutrophil activation as potential indicators for stroke risk and reperfusion failure The CLOTSAFE – Study (micro-CLOTs, Stroke risk, Activated neutrophils, reperfusion FailurE) |
non clinical, involving persons | monocentric | A | Prof. Dr. med. Susanne Wegener | University Hospital Zurich |
Department of Neurology, University Hospital Zurich (USZ), Zürich |
Kantonale Ethikkommission Zürich | 24.01.2025 | ||||||
| 2024-01352 | Characteristics and survival of children with severe life-threatening trauma in Switzerland | personal data/biological material | monocentric | PD Dr. med. Urs Pietsch | Kantonsspital St. Gallen |
KSSG, Klinik für operative Intensivmedizin, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 11.07.2024 | |||||||