| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-02517 | MS-Biomarker und ultralangfristiger Krankheitsverlauf – Analyse der Biobank II der Klinik für Neurologie des Universitätsspitals Basel | personal data/biological material | monocentric | Prof. Dr. med. Jens Kuhle | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.01.2025 | |||||||
| 2024-02516 | Implementation of a Standardized Algorithm for CoronarY CaLcificatiOn with PlaquE Modification using UltraSound Guidance to Improve Procedural and Clinical Outcomes | clinical trial | other clinical trials | multicentric | A | Prof. Barbara Stähli | Royal College of Surgeons in Ireland |
Universitätsspital Zürich, Zürich Kantonsspital St.Gallen, St.Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS) | 25.04.2025 | ||||
| 2024-02514 | Retrospective clinical evaluation of the Neodent® Ceramic Implant | personal data/biological material | monocentric | Prof. Dr. med. Dr. med. Dent. Philipp Metzler | Kantonsspital Aarau AG |
Kantonsspital Aarau AG, Klinik für Mund-, Kiefer- und Gesichtschirurgie, 5001 Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.01.2025 | |||||||
| 2024-02513 | Metabolomics for accelerated prediction in Patients with Pneumococcal/Bacterial Respiratory Infections | non clinical, involving persons | monocentric | A | Dr. Sylvain Meylan | Centre hospitalier universitaire vaudois (CHUV) |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.03.2025 | ||||||
| 2024-02512 | Genetic versus non-genetic unilateral retinoblastoma: clinical presentation, treatment, and outcome | personal data/biological material | monocentric | Dr Manuel Diezi | CHUV - Hématologie |
CHU Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.03.2025 | |||||||
| 2024-02511 | Learning tumor dynamics and early markers of immunotherapy response from PET/CT imaging | personal data/biological material | monocentric | Prof. John PRIOR | CHUV - Médecine nucléaire |
CHUV Service de médecine nucléaire et imagerie moléculaire, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.02.2025 | |||||||
| 2024-02510 | The frontal aslant tract and its possible role in language: a report on patients after low grade glioma surgery | personal data/biological material | monocentric | Prof. Dr. med. Kathleen Seidel |
Neurosurgery department, Inselspital, Bern |
Kantonale Ethikkommission Bern | 11.02.2025 | Study has ended | |||||||
| 2024-02509 | Diagnostic and Therapeutic Gaps in COPD Management: A Retrospective Cohort Study on GOLD Staging, Risk Classes, and Pharmacological Therapy in Hospitalized Patients with Acute Exacerbations | personal data/biological material | monocentric | PD Dr. med. Sabrina Jegerlehner | Allgemeine Innere Medizin Bürgerspital Solothurn |
Bürgerspital Solothurn, Klinik für Allgemeine Innere Medizin, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.01.2025 | |||||||
| 2024-02508 | Resection of the primary tumor vs. systemic treatment alone for patients with small intestinal neuroendocrine tumors and unresectable metastases: a retrospective, Europe-wide, pooled cohort study (Sur More ... | personal data/biological material | multicentric | Prof. Dr. med. Reto Kaderli | Inselspital |
Universitätsklinik für Viszerale Chirurgie und Medizin, Insespital Bern, Bern University Hospital of Basel, Basel Centre hospitalier universitaire vaudois (CHUV), Lausanne |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 04.02.2025 | ||||||
| 2024-02507 | Adhésion thérapeutique des enfants et des adolescent·es suivi·es à la consultation d’adhésion de la Pharmacie d’Unisanté [Therapeutic adherence of children and adolescents followed at the Unisanté Pha More ... | personal data/biological material | monocentric | PD MER Jérôme Berger | Unisanté |
Unisanté, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.01.2025 | Study has ended | ||||||
| 2024-02506 | AI assisted diagnosis of endometriosis based on transvaginal ultrasound | personal data/biological material | monocentric | Dr. med. Mark Ormos | Scanvio Medical AG |
Kantonsspital Baden AG, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.01.2025 | Study has ended | ||||||
| 2024-02505 | Exploring Patient Attitudes Towards Intravitreal Injections for Geographic Atrophy in dry AMD: A Survey Study | non clinical, involving persons | multicentric | A | Dr. med. Gábor Márk Somfai | Stadtspital Zürich |
Stadtspital Zürich, Zürich Gutblick, Wetzikon |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 11.07.2025 | |||||
| 2024-02504 | Natural history of cardiac transthyretin amyloidosis - mechanistic insights by multimodality imaging | non clinical, involving persons | monocentric | B | Dominik Benz | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 01.07.2025 | ||||||
| 2024-02503 | Development of a portable medical genetics laboratory: Initial testing with volunteers from Western Switzerland with HbS or HbC alleles | non clinical, involving persons | monocentric | A | Dr Cécile CHOUDJA OUABO-JEROME | Uni Bern |
INDEPENDANT, LAUSANNE |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.03.2025 | Study has ended | |||||
| 2024-02502 |
EORTC-LEGATO Lomustine with or without reirradiation for first progression of glioblastoma: a randomized phase III study |
clinical trial | drugs | phase 3 | multicentric | B | PD Dr. med. Emilie le Rhun | EORTC |
Universitätsspital Zürich, Zürich Istituto Oncologico della Svizzera Italian, Bellinzona |
Kantonale Ethikkommission Zürich | Comitato etico cantonale Ticino | 08.04.2025 | |||
| 2024-02501 | Cold snare unroofing of subepithelial lesions in the GI tract | personal data/biological material | monocentric | Dr. med. Bernhard Morell | Abteilung für Gastroenterologie |
Abteilung für Gastroenterologie, Stadtspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 04.04.2025 | Study has ended | ||||||
| 2024-02500 | Epidemiology and outcomes of acyclovir/foscarnet-refractory/resistant mucocutaneous HSV infections in allogeneic hematopoietic cell transplant recipients | personal data/biological material | multicentric | Dionysios Neofytos | HUG |
Hôpitaux Universitaires de Genève, Geneva University of Basel, Basel Universitätsspital Zürich, Zürich |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 24.01.2025 | ||||||
| 2024-02499 | Phase I/Ib, Open-label, Dose-escalating, Clinical and Pharmacokinetic Study of PM54 Administered Intravenously to Patients with Selected Advanced Solid Tumors | clinical trial | drugs | phase 1 | multicentric | C | Dr. Ioannis Metaxas | Pharma Mar, S.A. |
Spital Thurgau AG, including Kantonsspital Münsterlingen and Frauenfeld, Münsterlingen and Frauenfeld Ente Ospedaliero Cantonale ( EOC ); Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Ethikkommission Ostschweiz (EKOS) | Comitato etico cantonale Ticino | 19.06.2025 | |||
| 2024-02496 | 20230005_A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Subjects With Metastatic Castration-Resistant Prostate Cance More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr . Richard Cathomas | Amgen Inc |
Departement Innere Medizin, Onkologie und Haematologie, Kantonsspital Graubuenden, Chur Medizinische Onkologie, Inselspital Bern, Bern Klinik für Onkologie Hämatologie, HOCH Health Ostschweiz, Kantons More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 29.04.2025 | |||
| 2024-02495 | CESARCOM. Improving therapeutic communication during c-section to decrease patients’ anxiety and enhance professionals’ satisfaction. | non clinical, involving persons | monocentric | A | Dr Océane Pécheux | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.05.2025 | ||||||