| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-00003 | Full-root aortic valve replacement by Medtronic Freestyle xenografts: clinical outcomes, valvular hemodynamics, and incidence of structural abnormalities on cardiac computed tomography | personal data/biological material | monocentric | Pr Matthias E. W. Kirsch | CHUV - Chirurgie cardiaque |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.04.2023 | |||||||
| 2023-00002 | Outcome of AB0-incompatible living donor kidney transplantation | personal data/biological material | monocentric | Prof.Dr.med. Dickenmann |
Universitätsspital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.01.2023 | ||||||||
| 2023-00001 |
Retrospective analysis of main outcomes of patients participating in phase I clinical trials conducted at the Oncology Institute of Southern Switzerland |
personal data/biological material | monocentric | PD Dr. med Anastasios Stathis | Oncology Institute of Southern Switzerland |
Oncology Institute of Southern Switzerland, Bellinzona |
Comitato etico cantonale Ticino | 21.02.2023 | |||||||
| 2022-D0130 |
Non-Invasive MOnitoring in Transcathether Aortic Valve Implantation – A single-center, prospective, interventional study with the ClearSight® Finger Cuff NIMO – TAVI Study |
clinical trial | medical devices | monocentric | A1 | Dr. Thomas Nestelberger | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.02.2023 | |||||
| 2022-D0129 | MAPVIX: Mapping the uterine cervix stiffness of pregnant women at mid gestation | clinical trial | medical devices | multicentric | A1 | PD Dr. med. Katharina Quack Lötscher | Pregnolia AG |
University Hospital Zurich, Zurich gynosense AG, Bankstrasse 8 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 25.04.2023 | ||||
| 2022-D0128 | PANOVA-4: Pilot, Single arm Study of Tumor Treating Fields (TTFields, 150kHz) Concomitant with Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-Line Treatment for Metastatic Pancreatic Ductal Ade More ... | clinical trial | combination drugs/devices | multicentric | C2 | Dr. Marc Michael Küng | Novocure GmbH |
HFR Freiburg – Kantonsspital, Freiburg Inselspital, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 06.04.2023 | ||||
| 2022-D0127 | A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-264 in Subjects With Type 1 Diabetes Mellitus | clinical trial | combination drugs/devices | monocentric | C2 | Dr. med. Fadi Haidar | Vertex Pharmaceuticals Inc. |
HUG, Geneve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.04.2023 | |||||
| 2022-D0124 | CORNEAL SENSITIVITY IN SILICONE HYDROGEL CONTACT LENS WEAR | clinical trial | medical devices | monocentric | A1 | Prof Daniela Nosch | Institut d’optométrie FHNW |
Institut d’optométrie FHNW, Olten |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.03.2023 | Study has ended | ||||
| 2022-D0123 | Using Transcranial Alternating Current Stimulation with Starstim Home Device to Improve Executive Function in Youths with 22q11.2 deletion syndrome: A randomized double-blind sham-controlled study | clinical trial | medical devices | monocentric | C2 | Prof. Stephan Eliez | UNIGE |
UNIGE, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.04.2023 | yes | ||||
| 2022-D0122 | PERIOPERATIVE CONTINOUS GLUCOSE MONITORING (CGM) IN PANCREAS– A novel strategy to detect complications? | clinical trial | medical devices | monocentric | A1 | PD Dr. med. Patryk Kambakamba | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 17.03.2023 | |||||
| 2022-D0121 | Clinical performance study for use of the Vysis MET FISH Probe Kit for the identification of patients with EGFR mutated MET-amplified, locally advanced or metastatic non-small cell lung cancer who hav More ... | clinical trial | in vitro diagnostic medical devices | multicentric | C2 | Prof. Dr. med. Sacha Rothschild | AstraZeneca AB |
Kantonsspital Baden, Baden Universitätsspital Basel, Klinik für Onkologie Am Petersgraben 4 Stadtspital Zürich Triemli, Birmensdorferstrasse 497 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.02.2023 | ||||
| 2022-D0120 | Clinical Performance Study Plan for use of the MET (SP44) IHC Clinical Trial Assay in D5087C00001, A Phase III, Randomised, Open-Label Study of Savolitinib in Combination With Osimertinib Versus Plati More ... | clinical trial | in vitro diagnostic medical devices | multicentric | C2 | Prof. Dr. med Rothschild | AstraZeneca AB |
Kantonsspital Baden AG, Baden Universitätsspital Basel, Department of Medical Oncology, Petersgraben 4 Stadtspital Zürich Triemli, Birmensdorferstrasse 497 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.02.2023 | ||||
| 2022-D0119 | A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation | clinical trial | medical devices | monocentric | C1 | Prof. Dr. Tobias Reichlin | Boston Scientific International S.A. |
Inselspital - Universitätsspital, Bern |
Kantonale Ethikkommission Bern | 24.02.2023 | |||||
| 2022-D0117 | Diagnostic markers and neuromodulatory treatment approach with transcranial alternating current stimulation (tACS) for the Visual Snow Syndrome | clinical trial | medical devices | monocentric | C1 | Prof. Christoph Schankin | Inselgruppe AG |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 23.02.2023 | |||||
| 2022-D0116 | Prospective Comparison of Diagnostic Performance and Cost-effectiveness of US, Abbreviated MRI for Hepatocellular Carcinoma Screening | clinical trial | medical devices | monocentric | A1 | Dr. Naïk Vietti Violi | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.02.2023 | |||||
| 2022-D0115 | A multi-centric randomized clinical trial to assess the outcome of a collagen matrix for soft tissue augmentation around multiple implants restored with implant-supported micro-veneered or monolithic More ... | clinical trial | medical devices | monocentric | A1 | Professor Irena Sailer | Université de Genève |
Clinique Universitaire de Médecine Dentaire, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.03.2023 | |||||
| 2022-D0114 | A randomized controlled clinical trial to compare two collagen membranes for guided bone regeneration (GBR) around dental implants restored with monolithic zirconia single crowns using three different More ... | clinical trial | medical devices | monocentric | A1 | Dr. med. dent Malin Strasding | Université de Genève |
Université de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 07.02.2023 | |||||
| 2022-D0113 | Post-Market, Non-Randomized, Multicentre PMCF Study To Monitor The Safety And Performance Of Symani System In Microsurgical Reconstructive Procedures In A Real Life Setting | clinical trial | medical devices | monocentric | A1 | Prof. Nicole Lindenblatt | Medical Microinstruments, Inc. |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 24.01.2023 | |||||
| 2022-D0112 | Prospective, Randomized, Open, Comparison Study to Demonstrate the Performance and the Safety of Cardiac Microcurrent Therapy (C-MIC) System | clinical trial | medical devices | monocentric | C2 | Dr. David Santer | Berlin Heals GmbH |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.03.2023 | Study has ended | ||||
| 2022-D0111 | Bilateral External Torque CT, a novel diagnostic tool for detection of syndesmotic insufficiency - Part 2 and 3 | clinical trial | medical devices | monocentric | C2 | PD Dr. med. Stephan Wirth | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 28.03.2023 | |||||