| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00565 | Tenofovir alafenamide in chronic hepatitis B: A multicenter real-life cohort study (REAL-TAF) | personal data/biological material | multicentric | Prof. Nasser Semmo | Inselspital |
Inselspital, Bern HOCH Health Ostschweiz, St. Gallen Epatocentro Ticino, Lugano Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 23.07.2025 | ||||||
| 2025-00564 | Study of human islet function and islet cell interconversion for targeted diabetes therapies | personal data/biological material | monocentric | Prof. Pedro Herrera | UNIGE |
UNIGE, Dept. Genetic Medicine & Development, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 27.11.2025 | |||||||
| 2025-00563 | Quality of Life and Care of Vestibular Schwannomas | non clinical, involving persons | monocentric | A | Prof. Dr. med. Alexander Huber | Universitätsklinikum Hamburg-Eppendorf |
University of Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.07.2025 | ||||||
| 2025-00562 | Analyzing brain tissue, extracranial tissues and bodily fluids in corpses – a resource characterizing the immunobiology of the central nervous system | deceased persons | monocentric | Prof. Dr. Marian C. Neidert | H-OCH Health Ostschweiz, Cantonal Hospital St. Gallen |
H-OCH Health Ostschweiz, Cantonal Hospital of St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 27.03.2025 | |||||||
| 2025-00561 |
Home care workers’ health risks of exposure to heat waves: Solutions for human adaptation to climate change in the context of working life extension |
clinical trial | other clinical trials | multicentric | A | Prof. Dr. Isabel Baumann |
Zurich University of Applied Sciences, Winterthur SUPSI, Mendrisio |
Kantonale Ethikkommission Zürich | Comitato etico cantonale Ticino | 06.06.2025 | |||||
| 2025-00560 | Sling VS Brace after Arthroscopic Rotator Cuff Repair: Long-Term Results | non clinical, involving persons | monocentric | A | Prof. Dr.med. Christian Candrian | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 26.05.2025 | ||||||
| 2025-00559 | Predicting Treatment Outcomes in Patients With Clinical Depression and Comorbid Psychiatric Disorders | personal data/biological material | monocentric | Prof. Dr. med. Sebastian Olbrich | University Hospital of Psychiatry Zurich |
University Hospital of Psychiatry Zurich, Zurich |
Kantonale Ethikkommission Zürich | 23.05.2025 | |||||||
| 2025-00558 | Growing up with Cerebral Visual Impairment (CVI). A research-based approach to improve the school-based support system for children with CVI and their families. | non clinical, involving persons | multicentric | A | Prof. Dr. Florian Baier | University of Applied Sciences and Arts Northwestern Switzerland |
University of Applied Sciences and Arts Northwestern Switzerland, Muttenz Université de Fribourg, Fribourg |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.07.2025 | yes | ||||
| 2025-00557 | Lifestyle Physical Activity Coaching in Outpatients with Major Depressive Disorder (PACOUTPAT): Randomized Controlled Trial on Physical Activity, Depression and Quality of Life | clinical trial | other clinical trials | monocentric | A | PD Dr. Johannes Beck | Departement für Sport, Bewegung und Gesundheit |
Sonnenhalde AG, Riehen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.05.2025 | |||||
| 2025-00556 | Comparative long-term outcomes of pancreas versus islet of Langerhans transplantation: a nationwide cohort study | personal data/biological material | monocentric | Dr. Fadi Haidar |
Hopitaux universitaire de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.07.2025 | ||||||||
| 2025-00555 | A Novel Fracture of the First Metacarpal Bone: Clinical Features and Treatment Approaches | personal data/biological material | monocentric | Prof.Dr.med.Andreas Schweizer | Universitätsklinik Balgrist |
Balgrist University Hospital, Zurich |
Kantonale Ethikkommission Zürich | 08.08.2025 | |||||||
| 2025-00554 | Prospective Observational Cohort Study for Magnetic Resonance-Based Radiation Therapy Simulation, Planning, and Treatment | non clinical, involving persons | monocentric | A | Dr Sebastian M. Christ | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 28.11.2025 | ||||||
| 2025-00553 | Assessing the Dynamics of Immune and Blood-Brain Barrier Changes During Treatment of Depression | non clinical, involving persons | monocentric | A | PD Dr. med. Flurin Cathomas | Psychiatrische Universitätsklinik Zürich |
Psychiatrische Universitätsklinik Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.07.2025 | ||||||
| 2025-00552 | Periphere Sehleistung mit einer optischen Folie | non clinical, involving persons | monocentric | A | Dr. Martin Lörtscher | Fachhochschule Nordwestschweiz |
Fachhochschule Nordwestschweiz, INstitut für Optometrie, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 31.03.2025 | Study has ended | |||||
| 2025-00551 | Oral Bioavailability, Urinary Recovery and Acute Effects of Mescaline Hydrochloride in Healthy Participants | clinical trial | other clinical trials | monocentric | B | Dr. med. Lorenz Müller | Klinische Pharmakologie und Toxikologie, Universitätsspital Basel |
Division of Clinical Pharmacology and Toxicology, University Hospital Basel, CH-4056 Basel, Switzerland |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.05.2025 | |||||
| 2025-00550 | RetinaNet-CCS-Register gefördert durch die Jackstädt-Stiftung | personal data/biological material | monocentric | Prof. Dr. Nicolas Feltgen | Klinik für Augenheilkunde, Universitätsklinikum Freiburg |
Universitätssptital Basel, Augenklinik, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.06.2025 | |||||||
| 2025-00549 | Value of AI tools in the musculoskeletal radiology | personal data/biological material | monocentric | PD Dr. med Anna Lucja Falkowski | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 07.11.2025 | |||||||
| 2025-00548 | Retrospektive descriptive Datenanalyse der Kontrastmittel unterstützten Ultraschall-Untersuchungen an Hand vorliegender Befunde der Klinik für Innere Medizin am Universitätsspital Basel. | personal data/biological material | monocentric | Dr. Mark Kirsch |
Universitätsspital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.07.2025 | ||||||||
| 2025-00547 | The role of different brain areas in short-term consolidation of a balance task | non clinical, involving persons | monocentric | A | Prof. Dr. Wolfgang Taube | UNIFR - Sciences et médecine |
Université Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.05.2025 | ||||||
| 2025-00546 |
M25-540: A Phase 3b, Multicenter, Randomized, Open-Label Study of Risankizumab Compared to Vedolizumab for the Treatment of Adult Subjects With Moderate to Severe Ulcerative Colitis Who are Naïve to More ... |
clinical trial | drugs | phase 3 | multicentric | B | Prof. Dr. med. Stephan Brand | AbbVie Inc. |
HOCH Health Ostschweiz-Kantonsspital St. Gallen, 9007 St. Gallen Inselspital, Bauchzentrum Bern, 3010 Bern Luzerner Kantonsspital - Gastroenterologie und Hepatologie, 6000 Luzern 16 |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 15.05.2025 | |||