| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-00963 | 20220028_A Phase 1 First-in-Human Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 355 as Monotherapy and in Combination with Pembrolizumab in Subjects with Advanced Sol More ... | clinical trial | drugs | phase 1 | multicentric | C | Martina Imbimbo | Amgen Inc |
Istituto Oncologico della Svizzera Italiana, Bellinzona HOCH Health Ostschweiz, St. Galen |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS) | 30.08.2024 | |||
| 2024-00962 | Pulmonary artery pulsatility index in aortic stenosis: detailed non-invasive and invasive characterization and prognostic impact after valve replacement (AS-PAPi) | personal data/biological material | monocentric | Prof. Dr. Micha Maeder | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 16.05.2024 | |||||||
| 2024-00961 | Practice of Fluid Therapy in Critically Ill Invasively Ventilated Patients (PRoFLUID)––an international multicenter observational cohort study | personal data/biological material | monocentric | Prof. Carmen Pfortmueller | Amsterdam University Medical Centers location ‘AMC’ |
Inselspital Bern, 3010 Bern |
Kantonale Ethikkommission Bern | 18.07.2024 | |||||||
| 2024-00960 | Influence of the menstrual cycle on the electrocardiogram and the autonomic nervous system in young women | non clinical, involving persons | monocentric | A | Prof. Dr. Christian Müller | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.06.2024 | yes | |||||
| 2024-00959 | The MUSICare Project: Effects of Differentiated Music Exposure on Exercise-Related Affect Among Cardiac Rehabilitation Inpatients | clinical trial | other clinical trials | monocentric | A | Medical Doctor Elena Tessitore | University Hospital of Geneva |
Cardiology and Internal Medicine and rehabilitation, Hospital “Beau-Séjour”, Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 04.11.2024 | |||||
| 2024-00957 | RECOVER: Investigation into the Consequences of Opioid Medication Use on Neurological Recovery and Functioning in Acute Management of Spinal Cord Injury | personal data/biological material | monocentric | PD Dr Marija Glisic | Swiss Paraplegic Research |
Swiss Paraplegic Research, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.06.2024 | |||||||
| 2024-00955 | Tackling domain shifts in pediatric neuroimaging: bridging advanced computational MR techniques and clinical practice | non clinical, involving persons | monocentric | A | Meritxell Bach Cuadra | CHUV - CIBM PET03/02/21046 |
CIBM, Radiology Department, CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.06.2024 | ||||||
| 2024-00954 | Überleben nach Magentumorresektion in Abhängigkeit der perioperativen Chemotherapie unter Berücksichtigung der Lebensqualität - Magenkarzinom Studie - Unterschied zwischen unterschiedlichen Chemothera More ... | personal data/biological material | monocentric | PD. Ignazio Tarantino, MD, MSc |
Department of General, Visceral, Endocrine, and Transplantation Surgery, Kantonsspital St. Gallen, Switzerland, St Gallen |
Ethikkommission Ostschweiz (EKOS) | 13.05.2024 | ||||||||
| 2024-00953 | SonoML: Classification of Ultrasound Examinations in Emergency Medicine Using Machine Learning | personal data/biological material | monocentric | Prof. Dr. med. Gert Krummrey | Inselspital, Universitätsklinik für Notfallmedizin |
Inselspital, Universitätsklinik für Notfallmedizin, Bern |
Kantonale Ethikkommission Bern | 27.06.2024 | |||||||
| 2024-00950 | 3D Segmentationen zur Analyse der Frakturmorphologie von proximalen Humerus-Frakturen | personal data/biological material | monocentric | PD Dr. Michael Schär | Inselspital Bern |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 19.07.2024 | |||||||
| 2024-00947 | Investigation of brain blood flow changes in acute ischemic stroke patients after endovascular thrombectomy | non clinical, involving persons | monocentric | A | MD PhD Jorn Fierstra | University Hospital Zurich, Department of Neurosurgery |
University Hospital Zurich, Department of Neurosurgery, Zurich |
Kantonale Ethikkommission Zürich | 18.10.2024 | ||||||
| 2024-00946 | AI-assisted migraine education: efficacy, safety and patients’ acceptance | clinical trial | other clinical trials | monocentric | A | Prof. Chiara Zecca | Neurocenter of Southern Switzerland |
Neurocenter of Southern Switzerland, Lugano |
Comitato etico cantonale Ticino | 10.01.2025 | |||||
| 2024-00945 |
20230016 - A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Tarlatamab Therapy in Subjects With Limited-Stage Small-Cell Lung Cancer (LS-SCLC) who Have not Progressed Fol More ... |
clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Sacha Rothschild | Amgen Inc. |
Zentrum für Onkologie / Hämatologie Kantonsspital Baden, Baden Universitätsklinik für Medizinische Onkologie Inselspital, Bern Universitätsspital Basel, Basel Ente Ospedaliero Cantonale (EOC), Istitu More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Comitato etico cantonale Ticino | 11.07.2024 | |||
| 2024-00944 | Surgical outcomes after mastectomy with immediate implant-based breast reconstruction (IBBR) - A Retrospective Review. | personal data/biological material | monocentric | PD Dr Carlo M. Oranges, MD, PhD |
Department of Plastic, Reconstructive, and Aesthetic Surgery, Geneva University Hospitals, Geneva University, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.06.2024 | ||||||||
| 2024-00943 | Retrospective monocentric analysis of periprosthetic fractures of the greater trochanter (Vancouver AG) | personal data/biological material | monocentric | Professor Daniel Wagner | CHUV - Traumatologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.05.2024 | |||||||
| 2024-00942 | Validation of the Basel version of the Awareness of Social Inference Test – Theory of Mind (BASIT-ToM) in patients with mild Alzheimer's disease dementia | non clinical, involving persons | monocentric | A | Prof. Dr. med. Marc Sollberger | University Department of Geriatric Medicine FELIX PLATTER |
Memory Clinic, University Center for Medicine of Aging FELIX PLATTER, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.06.2024 | ||||||
| 2024-00941 | Evaluation quantitativer Ultraschall Techniken bei Kindern | personal data/biological material | monocentric | Prof. Dr. Christian Kellenberger | Universitätskinderspital Zürich |
Universitätskinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 09.08.2024 | |||||||
| 2024-00939 | SOUND - Secondary data analysis of current treatment practice of chronic spontaneous urticaria patients in Switzerland | personal data/biological material | multicentric | Dr. med. Claudia Lang | Novartis Pharma Schweiz AG |
Universitätsspital Zürich, Dermatologische Klinik, Zürich Universitätsspital Basel, Dermatologie, Basel Luzerner Kantonsspital, Zentrum für Dermatologie und Allergologie, Luzern CHUV, Service d'immuno More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.07.2024 | ||||||
| 2024-00938 | Energy Management for persons living with Long COVID (EMERGE) | non clinical, involving persons | multicentric | A | Dr. Ruth Hersche | University of Applied Sciences and Arts of Southern Switzerland (SUPSI) |
University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Manno Inselspital, Universitaetsklinik fuer Rheumatologie, 3010 Bern REHAB, Klinik fur Neurorehabilitation, 4055 Basel Universi More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 30.07.2024 | |||||
| 2024-00937 | Indicateurs cliniques pour la prévention des traumatismes acoustiques chez les musiciens | personal data/biological material | monocentric | PD Dr Angélica Pérez Fornos | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.11.2024 | |||||||