| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00415 | A Double-Blind, Placebo-Controlled, Multicenter, Randomized Phase 3 Trial Evaluating the Efficacy and Safety of Felzartamab in Kidney Transplant Recipients with Late Antibody-Mediated Rejection (AMR) More ... | clinical trial | drugs | phase 3 | multicentric | C | Matthias Hannes Diebold | Biogen Idec Research Limited |
Universitätsspital Basel, Basel University Hospital Zurich, Zurich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 24.07.2025 | |||
| 2025-00413 | SwissNeuroRehab – High Dose High Intensity Neurorehabilitation along the Continuum of Care | clinical trial | other clinical trials | multicentric | A | Olivier Bill | CHUV |
CHUV, Lausanne LLUI, vitznau kliniken valens, valens Swiss Rehabilitation Sarl, Sullens USZ, Zürich |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.12.2025 | ||||
| 2025-00411 | CA224-1093: A Phase 3, Randomized, Open-label Study of Nivolumab + Relatlimab Fixed-dose Combination with Chemotherapy Versus Pembrolizumab with Chemotherapy as First-line Treatment for Participants w More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Andreas Schmitt | Bristol-Myers Squibb Services Unlimited Company |
Universitätsspital Basel, Basel Spital Thurgau AG, 8596 Münsterlingen Ente Ospedaliero Cantonale ( EOC ), 6500 Bellinzona Centre Hospitalier Universitaire Vaudois (CHUV) Département d'oncologie UNIL R More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 02.07.2025 | |||
| 2025-00410 | Feasibility of Endovascular Recanalization for Symptomatic Chronic Intradural Large Vessel Occlusions - Re-CHILL Study | personal data/biological material | multicentric | Prof. Dr. med. Jan Gralla | University Hospital Bern, Inselspital |
University Hospital Bern, Inselspital, Bern University Hospital Zürich, Zürich |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 13.05.2025 | ||||||
| 2025-00409 | Haemostatic abnormalities in cirrhosis: Platelet functions and fibrin clot structure | non clinical, involving persons | monocentric | A | Prof. Dr med Lorenzo Alberio | CHUV - Hématologie |
Lausanne University Hospital (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.06.2025 | ||||||
| 2025-00407 | Kontrastempfindlichkeit bei Personen mit Glaukom | non clinical, involving persons | monocentric | A | Prof. Dr. Daniela Nosch | Fachhochschule Nordwestschweiz |
Institut für Optometrie, FHNW, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.03.2025 | Study has ended | |||||
| 2025-00406 | Determining the short- to medium-term outcome after minimally invasive sonography guided release of the carpal tunnel compared to standard-of-care open and endoscopic techniques: a randomized controll More ... | clinical trial | other clinical trials | monocentric | A | Dr. med. Saskia Kamphuis | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.05.2025 | |||||
| 2025-00405 | Torsionsmessung der unteren Extremitäten bei Kindern und Jugendlichen: Dosisvergleich zwischen CT mit Zinnfilter und EOS | non clinical, involving persons | monocentric | A | PD Dr. med. Stephan Wälti | Kantonsspital St. Gallen und Ostschweizer Kinderspital |
Kantonsspital St. Gallen und Ostschweizer Kinderspital, Klinik für Radiologie und Nuklearmedizin, 9000 St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 06.03.2025 | yes | |||||
| 2025-00404 | Detection of biomarkers in oral and oropharyngeal squamous cell carcinoma using breath analysis with respect to the oral microbiome by comparing cancer patients before curative treatment and during on More ... | non clinical, involving persons | monocentric | A | Prof. Dr. med. Dr. med. dent. Harald Essig | University Hospital Zurich, Department for Cranio- Maxillofacial Surgery |
University Hospital Zürich, Department for Cranio- Maxillofacialsurgery, Zürich |
Kantonale Ethikkommission Zürich | 05.08.2025 | ||||||
| 2025-00403 | Travelers Visiting Friends and Relatives’ and their Perspectives and Experiences on Travel related Health: A Reflexive Thematic Analysis | non clinical, involving persons | monocentric | A | Dr. sc. med./Nicca/Dunja | Institut für Epidemiologie, Biostatistik und Prävention |
UZH Institut für Epidemiologie, Biostatistik und Prävention, Zürich |
Kantonale Ethikkommission Zürich | 11.07.2025 | ||||||
| 2025-00402 | Al-based Analysis of multimodal imaging data for patients with retinal vascular disease | personal data/biological material | monocentric | Prof. Dr. Dr. Daniel Barthelmes | University of Zurich and University Hospital Zurich |
University Hospital Zurich and University Zurich, Zurich |
Kantonale Ethikkommission Zürich | 20.06.2025 | |||||||
| 2025-00401 | Early detection of oropharyngeal dysphagia in rehabilitation and follow-up care sectors – The EDOR-Care study | non clinical, involving persons | monocentric | A | Pre Marie-José Roulin | Hôpitaux Universitaires de Genève (HUG) |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.10.2025 | ||||||
| 2025-00400 |
Postoperative NSAID administration and bleeding risk in children undergoing elective cranial neurosurgical procedures |
personal data/biological material | monocentric | Prof. Dr. Jehuda Soleman | Neurochirurgie USB und UKBB |
Neurosurgery and Pediatric Neurosurgery, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.03.2025 | |||||||
| 2025-00398 | Correlation of Contrast Sensitivity and Low Luminance Visual Acuity with Multimodal Morphological Assessment in Non-Proliferative Diabetic Retinopathy | non clinical, involving persons | monocentric | A | PD Dr. med. Katja Hatz | Vista Augenklinik Binningen |
Vista Augenklinik Binningen, Binningen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.04.2025 | ||||||
| 2025-00397 | Systematic review of donor-derived-infections after a solid organ transplantation between 2012 and 2023: An analysis of the Swiss Transplant Cohort Study | personal data/biological material | multicentric | Prof. Dr. Nicolas Müller | University Hospital of Zürich, Division of Infectious Diseases and Hospital Epidemiology |
Universitätsspital Zürich Klinik für Infektiologie und Spitalhygiene, Zürich University Hospital Berne, Berne University Hospital Basel, Division of Infectious Diseases and Hospital Epidemiology, Base More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 24.10.2025 | ||||||
| 2025-00396 | Surveillance of pancreatic cystic lesions: outcomes in a Swiss community hospital | personal data/biological material | monocentric | Prof. Dr.med. Radu Tutuian |
Bürgerspital Solothurn, Solothurn |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.05.2025 | ||||||||
| 2025-00395 | Neurofilament EXpression in NeUrofibromatosiS Type 1 NEXUS Study | non clinical, involving persons | monocentric | A | Dr med Patricia Elsa Dill | UKBB |
UKBB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.04.2025 | yes | |||||
| 2025-00394 | Revolutionizing Aortic Root Enlargement: A Retrospective Study showing the efficacy and safety of “H-Incision Technique" | personal data/biological material | monocentric | Professor Christoph Huber | Hôpitaux Universitaires de Genève, Service de Chirurgie Cardio-Vasculaire |
Hôpitaux Universitaires de Genève, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.03.2025 | |||||||
| 2025-00389 | Identifizierung von Gen- und Proteinexpressionsmustern in Mastozytose-Hautproben: Ansätze für personalisierte und gezielte Therapien | personal data/biological material | monocentric | Prof. Dr. Karin Hartmann | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.04.2025 | |||||||
| 2025-00388 | Post-Breast Reconstruction Dermatitis – Differential Diagnosis and Treatment | personal data/biological material | monocentric | Dr.med Isabel Zucal | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 22.05.2025 | |||||||